Resources

A CONTINUOUS SCIENTIFIC OUTPUT

As a leading CRO in biosafety testing based on NGS assays for viral safety and genetic characterization at a GMP grade, PathoQuest is committed to share scientific researches and data evidence on its portfolio of assays.

Our experts in genome sequencing, virology and bioinformatics are continuously aiming to issue scientific overviews of our NGS QC biosafety assays.

  • Evaluation of a viral transcriptome Next Generation Sequencing assay as an alternative to animal assays for viral safety testing of cell substrates
Pascale Beurdeley-Fehlbaum 1, Matthew Pennington 2, Nicolas Hégerlé 1, Mélanie Albert 1, Amy Bennett 3, Justine Cheval 1, Allison Clark 3, Stéphane Cruveiller 1, Céline Desbrousses 1, Janalyn Frederick 4, Edwige Gros 1, Kathryn Hunter 3, Tareq Jaber 3, Madison Gaiser 5, Ophélie Jouffroy 1, Arnaud Lamamy 1, Mickael Melkowski 1, Jennifer Moro 3, Paula Niksa 3, Shenba Pillai 3, Marc Eloit 6, Horst Ruppach 3

2023 Aug

Arifa S. Khanᵃ,∗, Johannes Blümelᵇ, Dieter Deforceᶜ, Marion F. Gruberᵃ, Carmen Jungbäckᵈ,ᵉ ᶠ,¹ avid Mackayᵍ, Jelle Matthijnssensʰ, Maureen O'Learyⁱ,²,stiaan Theunsᶜ, Joseph Victoriaʲ, Pieter Neelsᵈ

2020 Sep

Céline Desbrousses 1, Fabienne Archer 2, Adélie Colin 3, Alexandra Bobet-Erny 2, Angélique Champavère 2, Edwige Gros 1, Pascale Beurdeley 1, Stéphane Cruveiller 1, Florence Tardy 3, Marc Eloit 4

2020 May

    • Adventitious Virus Detection in Cells by High-Throughput Sequencing of Newly Synthesized RNAs: Unambiguous Differentiation of Cell Infection from Carryover of Viral Nucleic Acids
Justine Cheval,a Erika Muth,a Gaëlle Gonzalez,b Muriel Coulpier,b Pascale Beurdeley,a Stéphane Cruveiller,a and Marc Eloitcorresponding authora,c,d

2019 May-Jun

    • Use of a new RNA next generation sequencing approach for the specific detection of virus infection in cells
Audrey Brussel 1, Kerstin Brack 2, Erika Muth 3, Rudolf Zirwes 3, Justine Cheval 3, Charles Hebert 3, Jean-Marie Charpin 3, Alice Marinaci 2, Benoit Flan 1, Horst Ruppach 2, Pascale Beurdeley 3, Marc Eloit 4

2019 May

    • Aetiology of acute meningoencephalitis in Cambodian children, 2010-2013
Paul F Horwood 1, Veasna Duong 1, Denis Laurent 2, Channa Mey 1, Heng Sothy 2, Ky Santy 2, Beat Richner 2, Seiha Heng 3, Sopheak Hem 3, Justine Cheval 4, Christopher Gorman 1, Philippe Dussart 1, Menno D de Jong 5, Alexandra Kerleguer 3, Bertrand Guillard 3, Bernadette Murgue 6, Marc Lecuit 7, Xavier de Lamballerie 8, Jeremy J Farrar 9, Arnaud Tarantola 10, Marc Eloit 4 7, Philippe Buchy 1 11

2017 May

    • Viral metagenomics and blood safety
V Sauvage 1, M Eloit 2

2016 Feb

    • The potential of whole genome NGS for infectious disease diagnosis
Marc Lecuit 1, Marc Eloit 2 3

2015 Nov

    • Analysis by high throughput sequencing of Specific Pathogen Free eggs
Léa Gagnieur 1, Justine Cheval 2, Marielle Cochet 3, Emmanuel Breard 3, Marlène Gratigny 2, Charles Hébert 2, Erika Muth 2, Cyril Viarouge 3, Marine Dumarest 1, Muriel Coulpier 3, Marc Eloit 4

2014 Jul

    • The diagnosis of infectious diseases by whole genome next generation sequencing: a new era is opening
Marc Lecuit 1, Marc Eloit 2

2014 Mar

Flyers

iDTECT® IDENTITY TESTING
iDTECT® INTEGRATION SITE ANALYSIS
iDTECT® VIRUS TESTING AND GENETIC CHARACTERIZATION OF PRODUCTION CELL LINES FOR CULTURED MEAT
iDTECT® TRANSCRIPTOME ANALYSIS
iDTECT® VIROME
HLA GENOTYPING with iDTECT®

Application Notes

REPLACING THE MAP, HAP, RAP WITH NGS iDTECT® TRANSCRIPTOME ASSAY
GMP Viral Vector and Plasmid Identity Testing with iDTECT® Next Generation Sequencing

Case Studies

CLONALITY INVESTIGATION FOR A CHO PRODUCTION CELL LINE USING iDTECT® INTEGRATION SITE ANALYSIS

Posters

Unveiling Recombinant Cell Line Mysteries: Nanopore Cas9- Sequencing for iDTECT® Integration Site Analysis (ISA) in CHO Cells
Integration Site Analysis (ISA) Assay - Oct 2023

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Genetic Characterization of Gene Therapy Vectors & Vaccines by Next Generation Sequencing (NGS) - May 2023

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Applications of Next Generation Sequencing for Viral Safety in Light of ICH Q5A R2- Feb 2024

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Adventitious Agent Testing For MMV How Much Do We Really Know- Oct 2024

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Everything You Always Wanted to Know About NGS in Biosafety
Episode 1: Why Adopt NGS for Quality Control in Biopharma?
Nov 2024

New ICHQ5A Guideline Adoption
Nov 2023

Introducing iDTECT®, a unique NGS-based platform for QC biotesting
March 2024

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France

+33 (0)1 70 82 17 90

Biopark -Bâtiment B,
11, rue Watt
75013 Paris, France

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U.S.

+1 484 212 9360

466 Devon Park Dr
Wayne, PA 19087
United States

France

+33 (0)1 70 82 17 90

Biopark -Bâtiment B,
11, rue Watt
75013 Paris, France

How can PathoQuest help?

Name(Required)
By submitting this form, PathoQuest will use the personal data you provide to handle your request. Read our Privacy Notice for more information.(Required)
This field is for validation purposes and should be left unchanged.

Sign up for our latest news